6BCM

Structure of a Self-inhibited N475A variant of the Venezuelan Equine Encephalitis Virus (VEEV) nsP2 cysteine protease

6BCM の概要

• エントリーDOI: 10.2210/pdb6bcm/pdb
• 分子名称: Protease nsP2, GLYCEROL, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: alphavirus, nsp2, nonstructural protein, cysteine protease, self-inhibited, n475a, s-adenosyl-l-methionine methyltransferase, viral protein
• 由来する生物種: Venezuelan equine encephalitis virus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38505.95

構造登録者

Compton, J.R.,Legler, P.M. (登録日: 2017-10-20, 公開日: 2017-11-08, 最終更新日: 2023-10-04)

• 主引用文献: Compton, J.R.,Mickey, M.J.,Hu, X.,Marugan, J.J.,Legler, P.M.; Mutation of Asn-475 in the Venezuelan Equine Encephalitis Virus nsP2 Cysteine Protease Leads to a Self-Inhibited State.; Biochemistry, 56:6221-6230, 2017; PubMed: 29064679; DOI: 10.1021/acs.biochem.7b00746

実験手法

X-RAY DIFFRACTION (2.1 Å)