6BBD

Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol

Summary for 6BBD

Entry DOI	10.2210/pdb6bbd/pdb
Related	4DN8
Descriptor	Pulmonary surfactant-associated protein D, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
Functional Keywords	innate immunity, surfactant, n-linked glycan, c-type lectin, surfactant protein
Biological source	Sus scrofa (Pig)
Total number of polymer chains	1
Total formula weight	17997.89
Authors	van Eijk, M.,Rynkiewicz, M.J.,Khatri, K.,Leymarie, N.,Zaia, J.,White, M.R.,Hartshorn, K.L.,Cafarella, T.R.,van Die, I.,Hessing, M.,Seaton, B.A.,Haagsman, H.P. (deposition date: 2017-10-18, release date: 2018-05-23, Last modification date: 2023-10-04)
Primary citation	van Eijk, M.,Rynkiewicz, M.J.,Khatri, K.,Leymarie, N.,Zaia, J.,White, M.R.,Hartshorn, K.L.,Cafarella, T.R.,van Die, I.,Hessing, M.,Seaton, B.A.,Haagsman, H.P. Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. J. Biol. Chem., 293:10646-10662, 2018 Cited by PubMed: 29769321 DOI: 10.1074/jbc.RA117.001430 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.898 Å)

Structure validation