6BB4

Fab/epitope complex of mouse monoclonal antibody C5.2 targeting a phospho-tau epitope.

6BB4 の概要

• エントリーDOI: 10.2210/pdb6bb4/pdb
• 分子名称: Mouse monoclonal antibody C5.2 Fab light chain, Mouse monoclonal antibody C5.2 Fab heavy chain, Microtubule-associated protein tau, ... (5 entities in total)
• 機能のキーワード: monoclonal antibody, fab, tau, phosphorylation state -specific antibody, immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 150081.75

構造登録者

Chukwu, J.E.,Kong, X.-P. (登録日: 2017-10-16, 公開日: 2018-05-02, 最終更新日: 2019-12-18)

• 主引用文献: Chukwu, J.E.,Pedersen, J.T.,Pedersen, L.O.,Volbracht, C.,Sigurdsson, E.M.,Kong, X.P.; Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.; Sci Rep, 8:6209-6209, 2018; PubMed: 29670132; DOI: 10.1038/s41598-018-24276-4

実験手法

X-RAY DIFFRACTION (2.099 Å)