6BAH

Trastuzumab Fab v3 with 5-diphenyl meditope variant

Summary for 6BAH

Entry DOI	10.2210/pdb6bah/pdb
Related	6b9y 6b9z 6bae
Descriptor	Trastuzumab Fab light chain,Immunoglobulin kappa constant, Trastuzumab Fab heavy chain,IGH@ protein, Protein L, ... (6 entities in total)
Functional Keywords	monoclonal antibody, fab, immune system
Biological source	Mus musculus More
Total number of polymer chains	5
Total formula weight	61861.65
Authors	Bzymek, K.P.,King, J.D.,Williams, J.C. (deposition date: 2017-10-12, release date: 2018-09-05, Last modification date: 2023-11-15)
Primary citation	King, J.D.,Ma, Y.,Kuo, Y.C.,Bzymek, K.P.,Goodstein, L.H.,Meyer, K.,Moore, R.E.,Crow, D.,Colcher, D.M.,Singh, G.,Horne, D.A.,Williams, J.C. Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29:2074-2081, 2018 Cited by PubMed: 29763554 DOI: 10.1021/acs.bioconjchem.8b00284 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation