6BAA
Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide
Summary for 6BAA
Entry DOI | 10.2210/pdb6baa/pdb |
EMDB information | 7073 |
Descriptor | ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | katp, sur1, kir6.2, sulfonylurea receptor, metal transport |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 8 |
Total formula weight | 887921.93 |
Authors | Martin, G.M.,Yoshioka, C.,Shyng, S.L. (deposition date: 2017-10-12, release date: 2017-11-01, Last modification date: 2019-12-25) |
Primary citation | Martin, G.M.,Kandasamy, B.,DiMaio, F.,Yoshioka, C.,Shyng, S.L. Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM. Elife, 6:-, 2017 Cited by PubMed: 29035201DOI: 10.7554/eLife.31054 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.63 Å) |
Structure validation
Download full validation report