6B77

Structures of the two-chain human plasma factor XIIa co-crystallized with potent inhibitors

6B77 の概要

• エントリーDOI: 10.2210/pdb6b77/pdb
• 関連するPDBエントリー: 6B74
• 分子名称: Coagulation factor XII, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, [3-(1-aminoisoquinolin-6-yl)phenyl]boronic acid, ... (8 entities in total)
• 機能のキーワード: structural characterization of human plasma factor xiia in complexes with inhibitors, blood clotting
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28382.01

構造登録者

Dementiev, A.A.,Silva, A.,Yee, C.,Flavin, M.T.,Partridge, J.R. (登録日: 2017-10-03, 公開日: 2018-03-21, 最終更新日: 2023-10-04)

• 主引用文献: Dementiev, A.,Silva, A.,Yee, C.,Li, Z.,Flavin, M.T.,Sham, H.,Partridge, J.R.; Structures of human plasma beta-factor XIIa cocrystallized with potent inhibitors.; Blood Adv, 2:549-558, 2018; PubMed: 29519898; DOI: 10.1182/bloodadvances.2018016337

実験手法

X-RAY DIFFRACTION (2.37 Å)