6B6K

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3-one

Summary for 6B6K

• Entry DOI: 10.2210/pdb6b6k/pdb
• Related: 5CXQ
• Descriptor: Purine nucleoside phosphorylase, DIMETHYL SULFOXIDE, 6-methylpyridazin-3-ol, ... (4 entities in total)
• Functional Keywords: purine nucleoside phosphorylase, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 32092.52

Authors

Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G. (deposition date: 2017-10-02, release date: 2018-10-10, Last modification date: 2023-10-04)

• Primary citation: Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G.; Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 3-methylpyridazin-1-ium-6-olate; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.46 Å)