6B5S
Structure of PfCSP peptide 25 with human antibody CIS42
Summary for 6B5S
Entry DOI | 10.2210/pdb6b5s/pdb |
Related | 6B5P 6B5R |
Descriptor | CIS42 Fab Heavy chain, CIS42 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN, ... (7 entities in total) |
Functional Keywords | malaria, pfcsp, vaccine, antibodies, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 49245.92 |
Authors | Pancera, M.,Weidle, C. (deposition date: 2017-09-29, release date: 2018-03-21, Last modification date: 2019-01-09) |
Primary citation | Kisalu, N.K.,Idris, A.H.,Weidle, C.,Flores-Garcia, Y.,Flynn, B.J.,Sack, B.K.,Murphy, S.,Schon, A.,Freire, E.,Francica, J.R.,Miller, A.B.,Gregory, J.,March, S.,Liao, H.X.,Haynes, B.F.,Wiehe, K.,Trama, A.M.,Saunders, K.O.,Gladden, M.A.,Monroe, A.,Bonsignori, M.,Kanekiyo, M.,Wheatley, A.K.,McDermott, A.B.,Farney, S.K.,Chuang, G.Y.,Zhang, B.,Kc, N.,Chakravarty, S.,Kwong, P.D.,Sinnis, P.,Bhatia, S.N.,Kappe, S.H.I.,Sim, B.K.L.,Hoffman, S.L.,Zavala, F.,Pancera, M.,Seder, R.A. A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24:408-416, 2018 Cited by PubMed: 29554083DOI: 10.1038/nm.4512 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.983 Å) |
Structure validation
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