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Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6B5S

Structure of PfCSP peptide 25 with human antibody CIS42

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue IPA H 301

Chain	Residue
H	PRO147
H	GLU148
H	TYR176
H	NA323

site_id	AC2
Number of Residues	3
Details	binding site for residue IPA H 302

Chain	Residue
H	SER70
H	PHE71
H	NH4308

site_id	AC3
Number of Residues	2
Details	binding site for residue IPA H 303

Chain	Residue
H	HOH423
H	HOH463

site_id	AC4
Number of Residues	4
Details	binding site for residue IPA H 304

Chain	Residue
H	GLN39
H	ALA40
H	PRO41
H	VAL89

site_id	AC5
Number of Residues	3
Details	binding site for residue IPA H 305

Chain	Residue
H	TYR96
H	ASP101
L	NA317

site_id	AC6
Number of Residues	3
Details	binding site for residue IPA H 306

Chain	Residue
H	GLY26
H	TYR27
H	THR28

site_id	AC7
Number of Residues	2
Details	binding site for residue NH4 H 307

Chain	Residue
H	LYS19
H	SER70

site_id	AC8
Number of Residues	3
Details	binding site for residue NH4 H 308

Chain	Residue
H	IPA302
H	NH4318
H	HOH440

site_id	AC9
Number of Residues	1
Details	binding site for residue NH4 H 309

Chain	Residue
H	LYS206

site_id	AD1
Number of Residues	4
Details	binding site for residue NH4 H 310

Chain	Residue
H	ASN155
H	SER156
H	ASN197
H	HOH492

site_id	AD2
Number of Residues	3
Details	binding site for residue NH4 H 311

Chain	Residue
H	GLU148
H	ALA168
H	NH4315

site_id	AD3
Number of Residues	5
Details	binding site for residue NH4 H 312

Chain	Residue
H	PRO123
H	LYS210
H	GLU212
H	HOH410
H	HOH446

site_id	AD4
Number of Residues	4
Details	binding site for residue NH4 H 313

Chain	Residue
H	VAL68
H	GLN81
H	NH4318
H	HOH450

site_id	AD5
Number of Residues	4
Details	binding site for residue NH4 H 314

Chain	Residue
H	ARG38
H	GLU85
H	ASP86
H	HOH425

site_id	AD6
Number of Residues	5
Details	binding site for residue NH4 H 315

Chain	Residue
H	GLU148
H	PRO149
H	VAL150
H	NH4311
H	HOH525

site_id	AD7
Number of Residues	4
Details	binding site for residue NH4 H 316

Chain	Residue
H	TYR102
H	TRP103
H	NH4322
L	HOH403

site_id	AD8
Number of Residues	2
Details	binding site for residue NH4 H 317

Chain	Residue
H	HOH466
L	HOH410

site_id	AD9
Number of Residues	3
Details	binding site for residue NH4 H 318

Chain	Residue
H	NH4308
H	NH4313
H	HOH510

site_id	AE1
Number of Residues	2
Details	binding site for residue NH4 H 319

Chain	Residue
H	ARG38
H	GLU46

site_id	AE2
Number of Residues	1
Details	binding site for residue NH4 H 320

Chain	Residue
H	SER17

site_id	AE3
Number of Residues	1
Details	binding site for residue NH4 H 321

Chain	Residue
H	SER115

site_id	AE4
Number of Residues	3
Details	binding site for residue NH4 H 322

Chain	Residue
H	LEU4
H	TRP103
H	NH4316

site_id	AE5
Number of Residues	2
Details	binding site for residue NA H 323

Chain	Residue
H	IPA301
H	HOH437

site_id	AE6
Number of Residues	1
Details	binding site for residue NA H 324

Chain	Residue
H	LYS143

site_id	AE7
Number of Residues	3
Details	binding site for residue NA H 325

Chain	Residue
H	GLU46
H	NA328
H	HOH528

site_id	AE8
Number of Residues	2
Details	binding site for residue NA H 326

Chain	Residue
H	GLY55
H	HOH440

site_id	AE9
Number of Residues	1
Details	binding site for residue NA H 327

Chain	Residue
H	PRO14

site_id	AF1
Number of Residues	2
Details	binding site for residue NA H 328

Chain	Residue
H	PRO61
H	NA325

site_id	AF2
Number of Residues	5
Details	binding site for residue NA H 329

Chain	Residue
H	ASN197
H	VAL198
H	LYS206
H	VAL207
H	ASP208

site_id	AF3
Number of Residues	3
Details	binding site for residue IPA L 301

Chain	Residue
L	ASP85
L	TYR87
L	GLY100

site_id	AF4
Number of Residues	5
Details	binding site for residue IPA L 302

Chain	Residue
L	GLN37
L	ASP82
L	NH4308
L	NH4309
L	NA314

site_id	AF5
Number of Residues	2
Details	binding site for residue IPA L 303

Chain	Residue
L	ARG54
L	SER56

site_id	AF6
Number of Residues	3
Details	binding site for residue NH4 L 304

Chain	Residue
L	SER29
L	PHE30
L	ASN31

site_id	AF7
Number of Residues	2
Details	binding site for residue NH4 L 305

Chain	Residue
L	GLN109
L	PRO110

site_id	AF8
Number of Residues	4
Details	binding site for residue NH4 L 306

Chain	Residue
L	SER138
L	NA315
L	SER115
L	LEU136

site_id	AF9
Number of Residues	3
Details	binding site for residue NH4 L 307

Chain	Residue
L	ALA148
L	TRP149
L	VAL156

site_id	AG1
Number of Residues	4
Details	binding site for residue NH4 L 308

Chain	Residue
L	HIS39
L	GLU81
L	IPA302
L	NA314

site_id	AG2
Number of Residues	3
Details	binding site for residue NH4 L 309

Chain	Residue
L	SER59
L	ARG61
L	IPA302

site_id	AG3
Number of Residues	3
Details	binding site for residue NH4 L 310

Chain	Residue
H	HOH483
L	SER122
L	SER123

site_id	AG4
Number of Residues	3
Details	binding site for residue NH4 L 311

Chain	Residue
A	ASN5
L	GLU50
L	LYS53

site_id	AG5
Number of Residues	5
Details	binding site for residue NH4 L 312

Chain	Residue
L	ASP152
L	SER169
L	ASN170
L	ASN171
L	HOH426

site_id	AG6
Number of Residues	3
Details	binding site for residue NH4 L 313

Chain	Residue
L	GLU124
L	GLN127
L	HOH407

site_id	AG7
Number of Residues	4
Details	binding site for residue NA L 314

Chain	Residue
L	GLU81
L	LYS157
L	IPA302
L	NH4308

site_id	AG8
Number of Residues	4
Details	binding site for residue NA L 315

Chain	Residue
L	SER115
L	VAL116
L	THR117
L	NH4306

site_id	AG9
Number of Residues	1
Details	binding site for residue NA L 316

Chain	Residue
L	NA317

site_id	AH1
Number of Residues	3
Details	binding site for residue NA L 317

Chain	Residue
H	IPA305
L	HIS49
L	NA316

site_id	AH2
Number of Residues	3
Details	binding site for residue NA L 318

Chain	Residue
L	ALA80
L	GLU83
L	HOH447

site_id	AH3
Number of Residues	5
Details	binding site for residue NA L 319

Chain	Residue
H	HOH480
L	HIS38
L	PRO40
L	GLY41
L	HOH513

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Repeat: {"description":"5","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	3
Details	Repeat: {"description":"6","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

246704

PDB entries from 2025-12-24

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