6B5K

Mycobacterium tuberculosis RmlA in complex with Mg/dTTP

6B5K の概要

• エントリーDOI: 10.2210/pdb6b5k/pdb
• 分子名称: Glucose-1-phosphate thymidylyltransferase, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: nucleotidyltransferase, transferase, substrate, sugar-modifying
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 67112.08

構造登録者

Brown, H.A.,Holden, H.A. (登録日: 2017-09-29, 公開日: 2018-02-21, 最終更新日: 2023-10-04)

• 主引用文献: Brown, H.A.,Thoden, J.B.,Tipton, P.A.,Holden, H.M.; The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes.; Protein Sci., 27:441-450, 2018; PubMed: 29076563; DOI: 10.1002/pro.3333

実験手法

X-RAY DIFFRACTION (1.6 Å)