6B3M

The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin

6B3M の概要

• エントリーDOI: 10.2210/pdb6b3m/pdb
• 分子名称: Hemagglutinin HA1, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• 機能のキーワード: antibody, hemagglutinin, influenza, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: unidentified influenza virus; 詳細
• タンパク質・核酸の鎖数: 24
• 化学式量合計: 645832.19

構造登録者

Shore, D.A.,Yang, H.,Stevens, J. (登録日: 2017-09-22, 公開日: 2018-06-13, 最終更新日: 2023-10-04)

• 主引用文献: Nachbagauer, R.,Shore, D.,Yang, H.,Johnson, S.K.,Gabbard, J.D.,Tompkins, S.M.,Wrammert, J.,Wilson, P.C.,Stevens, J.,Ahmed, R.,Krammer, F.,Ellebedy, A.H.; Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge.; J. Virol., 92:-, 2018; PubMed: 29899095; DOI: 10.1128/JVI.00949-18

実験手法

X-RAY DIFFRACTION (3.92 Å)