6B0S

Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody

6B0S の概要

• エントリーDOI: 10.2210/pdb6b0s/pdb
• 分子名称: 1710 antibody, heavy chain, 1710 antibody, light chain, Circumsporozoite protein, ... (6 entities in total)
• 機能のキーワード: malaria, circumsporozoite protein, alpha thrombospondin type-1 repeat, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 56522.85

構造登録者

Scally, S.W.,Murugan, R.,Bosch, A.,Triller, G.,Wardemann, H.,Julien, J.P. (登録日: 2017-09-15, 公開日: 2017-11-08, 最終更新日: 2023-10-04)

• 主引用文献: Scally, S.W.,Murugan, R.,Bosch, A.,Triller, G.,Costa, G.,Mordmuller, B.,Kremsner, P.G.,Sim, B.K.L.,Hoffman, S.L.,Levashina, E.A.,Wardemann, H.,Julien, J.P.; Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.; J. Exp. Med., 215:63-75, 2018; PubMed: 29167197; DOI: 10.1084/jem.20170869

実験手法

X-RAY DIFFRACTION (1.95 Å)