6B09
Crystal structure of HsNUDT16 in complex with diADPR (soaked)
Summary for 6B09
Entry DOI | 10.2210/pdb6b09/pdb |
Related | 5VY2 5W6X 5W6Z 5WJI |
Descriptor | U8 snoRNA-decapping enzyme, [(2~{R},3~{S},4~{S},5~{S})-5-(6-aminopurin-9-yl)-4-[(2~{S},3~{S},4~{S},5~{S})-5-[[[[(2~{R},3~{R},4~{S},5~{S})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]oxy-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | nudix hydrolase, decapping enzyme, demodification of parylation, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 44776.51 |
Authors | Thirawatananond, P.,Gabelli, S.B. (deposition date: 2017-09-14, release date: 2019-01-09, Last modification date: 2024-03-13) |
Primary citation | Thirawatananond, P.,McPherson, R.L.,Malhi, J.,Nathan, S.,Lambrecht, M.J.,Brichacek, M.,Hergenrother, P.J.,Leung, A.K.L.,Gabelli, S.B. Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins. Sci Rep, 9:5940-5940, 2019 Cited by PubMed: 30976021DOI: 10.1038/s41598-019-39491-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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