6AXN
F95C Epi-isozizaene synthase
Summary for 6AXN
| Entry DOI | 10.2210/pdb6axn/pdb |
| Descriptor | Epi-isozizaene synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... (6 entities in total) |
| Functional Keywords | terpenoid cyclase, lyase |
| Biological source | Streptomyces coelicolor |
| Total number of polymer chains | 1 |
| Total formula weight | 44209.24 |
| Authors | Blank, P.N.,Barrow, G.H.,Christianson, D.W. (deposition date: 2017-09-07, release date: 2017-10-18, Last modification date: 2023-10-04) |
| Primary citation | Blank, P.N.,Barrow, G.H.,Chou, W.K.W.,Duan, L.,Cane, D.E.,Christianson, D.W. Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes. Biochemistry, 56:5798-5811, 2017 Cited by PubMed: 28967743DOI: 10.1021/acs.biochem.7b00895 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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