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6AXD

Structures of REV1 UBM2 domain complex with ubiquitin and with the first small-molecule that inhibits the REV1 UBM2-ubiquitin interaction

Summary for 6AXD
Entry DOI10.2210/pdb6axd/pdb
NMR InformationBMRB: 30340
DescriptorDNA repair protein REV1 (1 entity in total)
Functional Keywordsubiquitin-binding motif, structural protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight7813.63
Authors
Fujii, N.,Vanarotti, M. (deposition date: 2017-09-06, release date: 2018-06-27, Last modification date: 2024-05-01)
Primary citationVanarotti, M.,Grace, C.R.,Miller, D.J.,Actis, M.L.,Inoue, A.,Evison, B.J.,Vaithiyalingam, S.,Singh, A.P.,McDonald, E.T.,Fujii, N.
Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction.
J. Mol. Biol., 430:2857-2872, 2018
Cited by
PubMed: 29864443
DOI: 10.1016/j.jmb.2018.05.042
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

221716

数据于2024-06-26公开中

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