6AXD

Structures of REV1 UBM2 domain complex with ubiquitin and with the first small-molecule that inhibits the REV1 UBM2-ubiquitin interaction

6AXD の概要

• エントリーDOI: 10.2210/pdb6axd/pdb
• NMR情報: BMRB: 30340
• 分子名称: DNA repair protein REV1 (1 entity in total)
• 機能のキーワード: ubiquitin-binding motif, structural protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 7813.63

構造登録者

Fujii, N.,Vanarotti, M. (登録日: 2017-09-06, 公開日: 2018-06-27, 最終更新日: 2024-05-01)

• 主引用文献: Vanarotti, M.,Grace, C.R.,Miller, D.J.,Actis, M.L.,Inoue, A.,Evison, B.J.,Vaithiyalingam, S.,Singh, A.P.,McDonald, E.T.,Fujii, N.; Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction.; J. Mol. Biol., 430:2857-2872, 2018; PubMed: 29864443; DOI: 10.1016/j.jmb.2018.05.042

実験手法

SOLUTION NMR