6AWE

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-fluoro-6-(2-pyridin-2-ylethylamino)benzonitrile

Summary for 6AWE

• Entry DOI: 10.2210/pdb6awe/pdb
• Related: 5CXQ
• Descriptor: Purine nucleoside phosphorylase, DIMETHYL SULFOXIDE, 2-fluoro-6-{[2-(pyridin-2-yl)ethyl]amino}benzonitrile, ... (4 entities in total)
• Functional Keywords: purine nucleoside phosphorylase, transferase
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 32301.80

Authors

Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G. (deposition date: 2017-09-05, release date: 2018-09-12, Last modification date: 2023-10-04)

• Primary citation: Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G.; Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-fluoro-6-(2-pyridin-2-ylethylamino)benzonitrile; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)