6AW8

2.25A resolution domain swapped dimer structure of SAH bound catechol O-methyltransferase (COMT) from Nannospalax galili

6AW8 の概要

• エントリーDOI: 10.2210/pdb6aw8/pdb
• 分子名称: Catechol O-methyltransferase, CALCIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• 機能のキーワード: spalax, comt, s-adenosylmethionine binding, transferase
• 由来する生物種: Nannospalax galili
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 78425.59

構造登録者

Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Deng, Y.,Hanzlik, R.P.,Shams, I.,Moskovitz, J. (登録日: 2017-09-05, 公開日: 2018-09-12, 最終更新日: 2023-10-04)

• 主引用文献: Deng, Y.,Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Hanzlik, R.P.,Shams, I.,Moskovitz, J.; Crystal structure of the catechol-o-methyl transferase (COMT) enzyme of the subterranean mole rat (Spalax) and the effect of L136M substitution; To be published,

実験手法

X-RAY DIFFRACTION (2.25 Å)