6AVJ

Crystal structure of human Mitochondrial inner NEET protein (MiNT)/CISD3

Summary for 6AVJ

• Entry DOI: 10.2210/pdb6avj/pdb
• Descriptor: CDGSH iron-sulfur domain-containing protein 3, mitochondrial, FE2/S2 (INORGANIC) CLUSTER (3 entities in total)
• Functional Keywords: neet-fold, iron-sulfur cluster, mitochondria, metal binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 31709.08

Authors

Lipper, C.H.,Karmi, O.,Sohn, Y.S.,Darash-Yahana, M.,Lammert, H.,Song, L.,Liu, A.,Mittler, R.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A. (deposition date: 2017-09-02, release date: 2017-12-20, Last modification date: 2023-10-04)

• Primary citation: Lipper, C.H.,Karmi, O.,Sohn, Y.S.,Darash-Yahana, M.,Lammert, H.,Song, L.,Liu, A.,Mittler, R.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A.; Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells.; Proc. Natl. Acad. Sci. U.S.A., 115:272-277, 2018; PubMed: 29259115; DOI: 10.1073/pnas.1715842115

Experimental method

X-RAY DIFFRACTION (1.9 Å)