6AU4

Crystal structure of the major quadruplex formed in the human c-MYC promoter

Summary for 6AU4

• Entry DOI: 10.2210/pdb6au4/pdb
• Descriptor: DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), POTASSIUM ION (3 entities in total)
• Functional Keywords: oncogene, quadruplex, c-myc, promoter, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 14251.61

Authors

Stump, S.,Mou, T.C.,Sprang, S.R.,Natale, N.R.,Beall, H.D. (deposition date: 2017-08-30, release date: 2018-09-12, Last modification date: 2023-10-04)

• Primary citation: Stump, S.,Mou, T.C.,Sprang, S.R.,Natale, N.R.,Beall, H.D.; Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene.; PLoS ONE, 13:e0205584-e0205584, 2018; PubMed: 30312328; DOI: 10.1371/journal.pone.0205584

Experimental method

X-RAY DIFFRACTION (2.35 Å)