6AQB

Structure of the SH3 domain of MLK3 bound to peptide generated from phage display

Summary for 6AQB

Entry DOI	10.2210/pdb6aqb/pdb
Descriptor	Chimera protein of MLK3-SH3 and MIP (E.C.2.7.11.25), 1,2-ETHANEDIOL, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	mlk3, sh3, phage display, signalling protein, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	15954.36
Authors	Kall, S.K.,Lavie, A. (deposition date: 2017-08-19, release date: 2018-07-04, Last modification date: 2024-03-13)
Primary citation	Kokoszka, M.E.,Kall, S.L.,Khosla, S.,McGinnis, J.E.,Lavie, A.,Kay, B.K. Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3. J. Biol. Chem., 293:13553-13565, 2018 Cited by PubMed: 29980598 DOI: 10.1074/jbc.RA117.000262 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation