6AJG

Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SQ109

6AJG の概要

• エントリーDOI: 10.2210/pdb6ajg/pdb
• 分子名称: Drug exporters of the RND superfamily-like protein,Endolysin, N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine, DODECYL-BETA-D-MALTOSIDE, ... (4 entities in total)
• 機能のキーワード: membrane protein, transporter, rnd family, cell wall biosynthesis, drug target, hydrolase
• 由来する生物種: Mycobacterium smegmatis str. MC2 155; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 109314.03

構造登録者

Zhang, B.,Li, J.,Yang, X.L.,Wu, L.J.,Yang, H.T.,Rao, Z.H. (登録日: 2018-08-27, 公開日: 2018-12-26, 最終更新日: 2023-11-22)

• 主引用文献: Zhang, B.,Li, J.,Yang, X.,Wu, L.,Zhang, J.,Yang, Y.,Zhao, Y.,Zhang, L.,Yang, X.,Yang, X.,Cheng, X.,Liu, Z.,Jiang, B.,Jiang, H.,Guddat, L.W.,Yang, H.,Rao, Z.; Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.; Cell, 176:636-648.e13, 2019; PubMed: 30682372; DOI: 10.1016/j.cell.2019.01.003

実験手法

X-RAY DIFFRACTION (2.604 Å)