6AJ4
Crystal structure of the DHR-2 domain of DOCK7 in complex with Cdc42
Summary for 6AJ4
Entry DOI | 10.2210/pdb6aj4/pdb |
Descriptor | Dedicator of cytokinesis protein 7, Cell division control protein 42 homolog (2 entities in total) |
Functional Keywords | dock, gef, dhr-2, gtpase, rho, rac, cdc42, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 221356.44 |
Authors | Kukimoto-Niino, M.,Shirouzu, M. (deposition date: 2018-08-27, release date: 2019-03-20, Last modification date: 2023-11-22) |
Primary citation | Kukimoto-Niino, M.,Tsuda, K.,Ihara, K.,Mishima-Tsumagari, C.,Honda, K.,Ohsawa, N.,Shirouzu, M. Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27:741-, 2019 Cited by PubMed: 30853411DOI: 10.1016/j.str.2019.02.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.256 Å) |
Structure validation
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