6AJ4

Crystal structure of the DHR-2 domain of DOCK7 in complex with Cdc42

Summary for 6AJ4

• Entry DOI: 10.2210/pdb6aj4/pdb
• Descriptor: Dedicator of cytokinesis protein 7, Cell division control protein 42 homolog (2 entities in total)
• Functional Keywords: dock, gef, dhr-2, gtpase, rho, rac, cdc42, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 221356.44

Authors

Kukimoto-Niino, M.,Shirouzu, M. (deposition date: 2018-08-27, release date: 2019-03-20, Last modification date: 2023-11-22)

• Primary citation: Kukimoto-Niino, M.,Tsuda, K.,Ihara, K.,Mishima-Tsumagari, C.,Honda, K.,Ohsawa, N.,Shirouzu, M.; Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor.; Structure, 27:741-, 2019; PubMed: 30853411; DOI: 10.1016/j.str.2019.02.001

Experimental method

X-RAY DIFFRACTION (3.256 Å)