6AGX
The cocrystal structure of FGFR2 bound with compound 14 harboring 5H-pyrrolo[2,3-b]pyrazine scaffold
Summary for 6AGX
Entry DOI | 10.2210/pdb6agx/pdb |
Descriptor | Fibroblast growth factor receptor 2, ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1H-imidazol-1-yl]acetate (2 entities in total) |
Functional Keywords | tyrosine-protein kinase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 140196.14 |
Authors | Xiong, B. (deposition date: 2018-08-15, release date: 2019-08-21, Last modification date: 2023-11-22) |
Primary citation | Xiong, B. The cocrystal structure of FGFR2 bound with compound 14 harboring 5H-pyrrolo[2,3-b]pyrazine scaffold To be published, |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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