6AGO
Crystal structure of MRG15-ASH1L Histone methyltransferase complex
Summary for 6AGO
Entry DOI | 10.2210/pdb6ago/pdb |
Descriptor | Histone-lysine N-methyltransferase ASH1L, Mortality factor 4 like 1, S-ADENOSYLMETHIONINE, ... (4 entities in total) |
Functional Keywords | nucleosome, methylation, activation, regulation, gene regulation, transferase-gene regulation complex, transferase/gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 101005.38 |
Authors | |
Primary citation | Lee, Y.,Yoon, E.,Cho, S.,Schmahling, S.,Muller, J.,Song, J.J. Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop. Structure, 27:846-, 2019 Cited by PubMed: 30827841DOI: 10.1016/j.str.2019.01.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.103 Å) |
Structure validation
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