6AGO

Crystal structure of MRG15-ASH1L Histone methyltransferase complex

6AGO の概要

• エントリーDOI: 10.2210/pdb6ago/pdb
• 分子名称: Histone-lysine N-methyltransferase ASH1L, Mortality factor 4 like 1, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• 機能のキーワード: nucleosome, methylation, activation, regulation, gene regulation, transferase-gene regulation complex, transferase/gene regulation
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 101005.38

構造登録者

Lee, Y.,Song, J. (登録日: 2018-08-13, 公開日: 2019-03-13, 最終更新日: 2024-03-27)

• 主引用文献: Lee, Y.,Yoon, E.,Cho, S.,Schmahling, S.,Muller, J.,Song, J.J.; Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop.; Structure, 27:846-, 2019; PubMed: 30827841; DOI: 10.1016/j.str.2019.01.016

実験手法

X-RAY DIFFRACTION (3.103 Å)