6AGL

Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli

Summary for 6AGL

DescriptorPhospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive (2 entities in total)
Functional Keywords3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahp synthase), escherichia coli, aromatic amino acid biosynthesis, feedback inhibition, allosteric regulation., biosynthetic protein
Biological sourceEscherichia coli (strain K12)
Total number of polymer chains2
Total molecular weight77691.8
Authors
Cui, D.,Qi, J.,Wen, T. (deposition date: 2018-08-13, release date: 2019-04-17)
Primary citation
Cui, D.,Deng, A.,Bai, H.,Yang, Z.,Liang, Y.,Liu, Z.,Qiu, Q.,Wang, L.,Liu, S.,Zhang, Y.,Shi, Y.,Qi, J.,Wen, T.
Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.
J. Struct. Biol., 2019
PubMed: 30946901 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsb.2019.04.001
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.291100 2.5% 11.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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