6ADV

Crystal Structure Analysis of the duplex containing the S2T(2',4'-BNA/LNA)G mismatch pairs

Summary for 6ADV

• Entry DOI: 10.2210/pdb6adv/pdb
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(9V9)P*GP*CP*G)-3' (2 entities in total)
• Functional Keywords: dna, lna, 2', 4'-bna, mismatched base pairs
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 7444.96

Authors

Aoyama, H.A.,Habuchi, T.H.,Yamaguchi, T.Y.,Obika, S.O. (deposition date: 2018-08-02, release date: 2019-03-27, Last modification date: 2023-11-22)

• Primary citation: Habuchi, T.,Yamaguchi, T.,Aoyama, H.,Horiba, M.,Ito, K.R.,Obika, S.; Hybridization and Mismatch Discrimination Abilities of 2',4'-Bridged Nucleic Acids Bearing 2-Thiothymine or 2-Selenothymine Nucleobase.; J. Org. Chem., 84:1430-1439, 2019; PubMed: 30632750; DOI: 10.1021/acs.joc.8b02863

Experimental method

X-RAY DIFFRACTION (1.96 Å)