6A9O

Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis

6A9O の概要

• エントリーDOI: 10.2210/pdb6a9o/pdb
• 分子名称: Superoxide dismutase [Cu-Zn], ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
• 機能のキーワード: dismutase, dimer, oxidation, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 161526.16

構造登録者

Manjula, R.,Padmanabhan, B. (登録日: 2018-07-14, 公開日: 2019-07-17, 最終更新日: 2023-11-22)

• 主引用文献: Manjula, R.,Unni, S.,Wright, G.S.A.,Bharath M M, S.,Padmanabhan, B.; Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis.; J.Biomol.Struct.Dyn., 37:3936-3946, 2019; PubMed: 30286701; DOI: 10.1080/07391102.2018.1531787

実験手法

X-RAY DIFFRACTION (2.5 Å)