6A7V

Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex

Summary for 6A7V

• Entry DOI: 10.2210/pdb6a7v/pdb
• Descriptor: Ribonuclease VapC11, Antitoxin VapB11, PENTAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: vapbc, endoribonuclease, trnase, rv1560-rv1561, toxin, toxin-antitoxin complex, toxin/antitoxin
• Biological source: Mycobacterium tuberculosis H37Rv; More
• Total number of polymer chains: 8
• Total formula weight: 89006.76

Authors

Deep, A.,Thakur, K.G. (deposition date: 2018-07-04, release date: 2018-10-10, Last modification date: 2023-11-22)

• Primary citation: Deep, A.,Tiwari, P.,Agarwal, S.,Kaundal, S.,Kidwai, S.,Singh, R.,Thakur, K.G.; Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation.; Nucleic Acids Res., 46:11639-11655, 2018; PubMed: 30329074; DOI: 10.1093/nar/gky924

Experimental method

X-RAY DIFFRACTION (1.67 Å)