6A7V

Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex

6A7V の概要

• エントリーDOI: 10.2210/pdb6a7v/pdb
• 分子名称: Ribonuclease VapC11, Antitoxin VapB11, PENTAETHYLENE GLYCOL, ... (5 entities in total)
• 機能のキーワード: vapbc, endoribonuclease, trnase, rv1560-rv1561, toxin, toxin-antitoxin complex, toxin/antitoxin
• 由来する生物種: Mycobacterium tuberculosis H37Rv; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 89006.76

構造登録者

Deep, A.,Thakur, K.G. (登録日: 2018-07-04, 公開日: 2018-10-10, 最終更新日: 2023-11-22)

• 主引用文献: Deep, A.,Tiwari, P.,Agarwal, S.,Kaundal, S.,Kidwai, S.,Singh, R.,Thakur, K.G.; Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation.; Nucleic Acids Res., 46:11639-11655, 2018; PubMed: 30329074; DOI: 10.1093/nar/gky924

実験手法

X-RAY DIFFRACTION (1.67 Å)