6INQ
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position)
Replaces: 6A5VSummary for 6INQ
Entry DOI | 10.2210/pdb6inq/pdb |
EMDB information | 6986 |
Descriptor | DNA-directed RNA polymerase subunit, RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III, RNA polymerase II subunit B12.5, ... (23 entities in total) |
Functional Keywords | nucleosome, chromatin, rna polymerase, transcription, transcription-rna-dna complex, transcription/rna/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 25 |
Total formula weight | 767723.68 |
Authors | Kujirai, T.,Ehara, H.,Fujino, Y.,Shirouzu, M.,Sekine, S.,Kurumizaka, H. (deposition date: 2018-10-26, release date: 2019-04-03, Last modification date: 2024-03-27) |
Primary citation | Kujirai, T.,Ehara, H.,Fujino, Y.,Shirouzu, M.,Sekine, S.,Kurumizaka, H. Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362:595-598, 2018 Cited by PubMed: 30287617DOI: 10.1126/science.aau9904 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.9 Å) |
Structure validation
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