6ZWB
Z-SBTub3 photoswitch bound to tubulin-DARPin D1 complex
Summary for 6ZWB
Entry DOI | 10.2210/pdb6zwb/pdb |
Descriptor | Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed Ankyrin Repeat Protein (DARPIN) D1, ... (8 entities in total) |
Functional Keywords | photopharmacology, microtubule dynamics, cytoskeleton, tubulin polymerisation inhibitor, colchicine, antimitotic, azobenzene, cell division, cell cycle, spatiotemporal control |
Biological source | synthetic construct More |
Total number of polymer chains | 3 |
Total formula weight | 119548.82 |
Authors | Wranik, M.,Weinert, T.,Olieric, N.,Gao, L.,Kraus, Y.C.M.,Bingham, R.,Ntouliou, E.,Ahlfeld, J.,Thorn-Seshold, O.,Steinmetz, M.O.,Standfuss, J. (deposition date: 2020-07-28, release date: 2020-12-23, Last modification date: 2024-01-31) |
Primary citation | Gao, L.,Meiring, J.C.M.,Kraus, Y.,Wranik, M.,Weinert, T.,Pritzl, S.D.,Bingham, R.,Ntouliou, E.,Jansen, K.I.,Olieric, N.,Standfuss, J.,Kapitein, L.C.,Lohmuller, T.,Ahlfeld, J.,Akhmanova, A.,Steinmetz, M.O.,Thorn-Seshold, O. A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton. Cell Chem Biol, 28:228-, 2021 Cited by PubMed: 33275880DOI: 10.1016/j.chembiol.2020.11.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.747 Å) |
Structure validation
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