6ZL1
Crystal structure of human serum albumin in complex with the MCL-1 neutralizing Alphabody CMPX-383B
Summary for 6ZL1
Entry DOI | 10.2210/pdb6zl1/pdb |
Related | 6ZIE |
Descriptor | Albumin, CMPX-383B (2 entities in total) |
Functional Keywords | de novo protein design, 3 helical antiparallel coiled coil, cell penetrating alphabody mcl-1 neutralizing alphabody, de novo protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 168643.47 |
Authors | Pannecoucke, E.,Savvides, S.N.,Desmet, J.,Lasters, I. (deposition date: 2020-06-30, release date: 2021-04-28, Last modification date: 2024-01-31) |
Primary citation | Pannecoucke, E.,Van Trimpont, M.,Desmet, J.,Pieters, T.,Reunes, L.,Demoen, L.,Vuylsteke, M.,Loverix, S.,Vandenbroucke, K.,Alard, P.,Henderikx, P.,Deroo, S.,Baatz, F.,Lorent, E.,Thiolloy, S.,Somers, K.,McGrath, Y.,Van Vlierberghe, P.,Lasters, I.,Savvides, S.N. Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting. Sci Adv, 7:-, 2021 Cited by PubMed: 33771865DOI: 10.1126/sciadv.abe1682 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.272 Å) |
Structure validation
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