6Z8G
Crystal structure of VSG13 soaked in 0.5 M used to phase VSG13 to solve the structure.
Summary for 6Z8G
Entry DOI | 10.2210/pdb6z8g/pdb |
Descriptor | Variant surface glycoprotein MITat 1.13, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... (5 entities in total) |
Functional Keywords | variant surface glycoprotein, immune recognition, immune evasion, trypanosomiasis, membrane protein |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 110974.04 |
Authors | Stebbins, C.E.,Hempelmann, A.,Van Straaten, M.,Zeelen, J. (deposition date: 2020-06-02, release date: 2021-03-17) |
Primary citation | Zeelen, J.,van Straaten, M.,Verdi, J.,Hempelmann, A.,Hashemi, H.,Perez, K.,Jeffrey, P.D.,Halg, S.,Wiedemar, N.,Maser, P.,Papavasiliou, F.N.,Stebbins, C.E. Structure of trypanosome coat protein VSGsur and function in suramin resistance. Nat Microbiol, 6:392-400, 2021 Cited by PubMed: 33462435DOI: 10.1038/s41564-020-00844-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
Download full validation report