6YJV
Crystal structure of unliganded MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with UDP-2-deoxy-2-fluoroglucose and biantennary pentasaccharide M592
This is a non-PDB format compatible entry.
Summary for 6YJV
Entry DOI | 10.2210/pdb6yjv/pdb |
Descriptor | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, ... (7 entities in total) |
Functional Keywords | transferase, carbohydrate, enzyme, n-glycosylation, glcnac |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 120921.89 |
Authors | Wu, L.,Darby, J.F.,Gilio, A.K.,Davies, G.J. (deposition date: 2020-04-04, release date: 2020-08-05, Last modification date: 2024-10-09) |
Primary citation | Darby, J.F.,Gilio, A.K.,Piniello, B.,Roth, C.,Blagova, E.,Rovira, C.,Hubbard, R.E.,Davies, G.J.,Wu, L. Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V Acs Catalysis, 2020 Cited by DOI: 10.1021/acscatal.0c02222PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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