6Y1Q
Cortistatin analog with improved immunoregulatory activity
Summary for 6Y1Q
Entry DOI | 10.2210/pdb6y1q/pdb |
NMR Information | BMRB: 34491 |
Descriptor | Analog 5, OCTANOIC ACID (CAPRYLIC ACID) (2 entities in total) |
Functional Keywords | peptidomimetic, analogue, medical chemistry, hormone |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 1926.37 |
Authors | |
Primary citation | Rol, A.,Todorovski, T.,Martin-Malpartida, P.,Escola, A.,Gonzalez-Rey, E.,Aragon, E.,Verdaguer, X.,Valles-Miret, M.,Farrera-Sinfreu, J.,Puig, E.,Fernandez-Carneado, J.,Ponsati, B.,Delgado, M.,Riera, A.,Macias, M.J. Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease. Nat Commun, 12:1869-1869, 2021 Cited by PubMed: 33767180DOI: 10.1038/s41467-021-22076-5 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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