6XXV
Crystal Structure of a computationally designed Immunogen S2_1.2 in complex with its elicited antibody C57
Summary for 6XXV
Entry DOI | 10.2210/pdb6xxv/pdb |
Related | 6S3D 6XWI |
Descriptor | Antibody C57, Heavy Chain, Antibody C57, Light Chain, S2_1.2, ... (4 entities in total) |
Functional Keywords | epitope scaffold, de novo designed protein, immunogen, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 134010.13 |
Authors | Yang, C.,Sesterhenn, F.,Correia, B.E.,Pojer, F. (deposition date: 2020-01-28, release date: 2020-04-22, Last modification date: 2024-01-24) |
Primary citation | Sesterhenn, F.,Yang, C.,Bonet, J.,Cramer, J.T.,Wen, X.,Wang, Y.,Chiang, C.I.,Abriata, L.A.,Kucharska, I.,Castoro, G.,Vollers, S.S.,Galloux, M.,Dheilly, E.,Rosset, S.,Corthesy, P.,Georgeon, S.,Villard, M.,Richard, C.A.,Descamps, D.,Delgado, T.,Oricchio, E.,Rameix-Welti, M.A.,Mas, V.,Ervin, S.,Eleouet, J.F.,Riffault, S.,Bates, J.T.,Julien, J.P.,Li, Y.,Jardetzky, T.,Krey, T.,Correia, B.E. De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368:-, 2020 Cited by PubMed: 32409444DOI: 10.1126/science.aay5051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.20116418766 Å) |
Structure validation
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