6XX4
Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
Summary for 6XX4
Entry DOI | 10.2210/pdb6xx4/pdb |
Related PRD ID | PRD_900086 |
Descriptor | Proto-oncogene tyrosine-protein kinase Src, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, ... (4 entities in total) |
Functional Keywords | beta barrel, sh3 domain, protein binding |
Biological source | Gallus gallus (Chicken) |
Total number of polymer chains | 1 |
Total formula weight | 8235.41 |
Authors | Camara-Artigas, A. (deposition date: 2020-01-26, release date: 2020-04-22, Last modification date: 2024-01-24) |
Primary citation | Plaza-Garrido, M.,Salinas-Garcia, M.C.,Martinez, J.C.,Camara-Artigas, A. The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25:621-634, 2020 Cited by PubMed: 32279137DOI: 10.1007/s00775-020-01785-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.05 Å) |
Structure validation
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