6XUI
Crystal structure of human phosphoglucose isomerase in complex with inhibitor
Summary for 6XUI
Entry DOI | 10.2210/pdb6xui/pdb |
Related | 6XUH |
Descriptor | Glucose-6-phosphate isomerase, 5-PHOSPHOARABINONIC ACID, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ... (5 entities in total) |
Functional Keywords | enzyme inhibitor, phosphate, monosaccharide, phosphoglucose isomerase, autocrine motility factor, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 254116.42 |
Authors | Li de la Sierra-Gallay, I.,Ahmad, L.,Plancqueel, S.,van Tilbeurgh, H.,Salmon, L. (deposition date: 2020-01-20, release date: 2020-07-29, Last modification date: 2024-01-24) |
Primary citation | Ahmad, L.,Plancqueel, S.,Lazar, N.,Korri-Youssoufi, H.,Li de la Sierra-Gallay, I.,van Tilbeurgh, H.,Salmon, L. Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies. Bioorg.Chem., 102:104048-104048, 2020 Cited by PubMed: 32682158DOI: 10.1016/j.bioorg.2020.104048 PDB entries with the same primary citation |
Experimental method |
Structure validation
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