6XSR
Crystal structure of GluA2 AMPA receptor in complex with trans-4-butylcyclohexane carboxylic acid (4-BCCA) inhibitor
Summary for 6XSR
Entry DOI | 10.2210/pdb6xsr/pdb |
Descriptor | Glutamate receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, trans-4-butylcyclohexane-1-carboxylic acid (3 entities in total) |
Functional Keywords | ampa receptor, ion channels, synapse, bcca, transport protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 363862.82 |
Authors | Yelshanskaya, M.V.,Singh, A.K.,Sobolevsky, A.I. (deposition date: 2020-07-16, release date: 2020-12-30, Last modification date: 2023-10-18) |
Primary citation | Yelshanskaya, M.V.,Singh, A.K.,Narangoda, C.,Williams, R.S.B.,Kurnikova, M.G.,Sobolevsky, A.I. Structural basis of AMPA receptor inhibition by trans-4-butylcyclohexane carboxylic acid. Br.J.Pharmacol., 179:3628-3644, 2022 Cited by PubMed: 32959886DOI: 10.1111/bph.15254 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.25 Å) |
Structure validation
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