6XL8
Crystal structure of 3-O-Sulfotransferase isoform 3 in complex with 8mer oligosaccharide with no 6S sulfation
Summary for 6XL8
Entry DOI | 10.2210/pdb6xl8/pdb |
Related | 6XKG |
Descriptor | Heparan sulfate glucosamine 3-O-sulfotransferase 3A1, beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose, beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ... (8 entities in total) |
Functional Keywords | sulfotransferase, enzyme, paps, heparan sulfate, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 67650.02 |
Authors | Pedersen, L.C.,Liu, J.,Wander, R. (deposition date: 2020-06-28, release date: 2021-06-23, Last modification date: 2023-10-18) |
Primary citation | Wander, R.,Kaminski, A.M.,Xu, Y.,Pagadala, V.,Krahn, J.M.,Pham, T.Q.,Liu, J.,Pedersen, L.C. Deciphering the substrate recognition mechanisms of the heparan sulfate 3- O -sulfotransferase-3. Rsc Chem Biol, 2:1239-1248, 2021 Cited by PubMed: 34458837DOI: 10.1039/d1cb00079a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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