6XIO
ADP-dependent kinase complex with fructose-6-phosphate and ADPbetaS
Summary for 6XIO
Entry DOI | 10.2210/pdb6xio/pdb |
Descriptor | ADP-dependent phosphofructokinase, 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE, 6-O-phosphono-beta-D-fructofuranose, ... (5 entities in total) |
Functional Keywords | ancestral protein reconstruction, adp-dependent sugar kinases family, glucokinase, phosphofructokinase, enzyme evolution, transferase |
Biological source | Methanosarcinales archaeon |
Total number of polymer chains | 1 |
Total formula weight | 58496.43 |
Authors | Munoz, S.,Gonzalez-Ordenes, F.,Fuentes, N.,Maturana, P.,Herrera-Morande, A.,Villalobos, P.,Castro-Fernandez, V. (deposition date: 2020-06-20, release date: 2021-01-20, Last modification date: 2023-10-18) |
Primary citation | Munoz, S.M.,Castro-Fernandez, V.,Guixe, V. Structure of an ancestral ADP-dependent kinase with fructose-6P reveals key residues for binding, catalysis, and ligand-induced conformational changes. J.Biol.Chem., 296:100219-100219, 2020 Cited by PubMed: 33839685DOI: 10.1074/jbc.RA120.015376 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.12 Å) |
Structure validation
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