6WCR
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)
Summary for 6WCR
Entry DOI | 10.2210/pdb6wcr/pdb |
Descriptor | Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | hemagglutinin, fusion inhibitors, small molecules, antiviral protein |
Biological source | Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) More |
Total number of polymer chains | 2 |
Total formula weight | 58578.26 |
Authors | kadam, R.U.,Wilson, I.A. (deposition date: 2020-03-31, release date: 2020-08-05, Last modification date: 2023-10-18) |
Primary citation | Yao, Y.,Kadam, R.U.,Lee, C.D.,Woehl, J.L.,Wu, N.C.,Zhu, X.,Kitamura, S.,Wilson, I.A.,Wolan, D.W. An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proc.Natl.Acad.Sci.USA, 117:18431-18438, 2020 Cited by PubMed: 32690700DOI: 10.1073/pnas.2006893117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
Download full validation report