6W0R
Human 8-oxoguanine glycosylase interrogating fully intrahelical undamaged DNA
Summary for 6W0R
Entry DOI | 10.2210/pdb6w0r/pdb |
Descriptor | N-glycosylase/DNA lyase, DNA (5'-D(P*CP*AP*GP*GP*TP*C)-3'), DNA (5'-D(P*CP*CP*TP*GP*G)-3'), ... (7 entities in total) |
Functional Keywords | hogg1, 8-oxog, encounter complex, interrogation complex, dna binding protein, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 38966.44 |
Authors | Shigdel, U.,Verdine, G. (deposition date: 2020-03-02, release date: 2020-09-23, Last modification date: 2023-10-11) |
Primary citation | Shigdel, U.K.,Ovchinnikov, V.,Lee, S.J.,Shih, J.A.,Karplus, M.,Nam, K.,Verdine, G.L. The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11:4437-4437, 2020 Cited by PubMed: 32895378DOI: 10.1038/s41467-020-18290-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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