6VTS

Crystal structure of G16S human Galectin-7 mutant in complex with lactose

Summary for 6VTS

• Entry DOI: 10.2210/pdb6vts/pdb
• Related PRD ID: PRD_900008
• Descriptor: Galectin-7, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, GLYCEROL, ... (4 entities in total)
• Functional Keywords: human galectin-7, lactose, sugar binding protein, g16s mutant
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 30952.63

Authors

Pham, N.T.H.,Calmettes, C.,Doucet, N. (deposition date: 2020-02-13, release date: 2021-08-25, Last modification date: 2023-10-11)

• Primary citation: Pham, N.T.H.,Letourneau, M.,Fortier, M.,Begin, G.,Al-Abdul-Wahid, M.S.,Pucci, F.,Folch, B.,Rooman, M.,Chatenet, D.,St-Pierre, Y.,Lague, P.,Calmettes, C.,Doucet, N.; Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7.; J.Biol.Chem., 297:101308-101308, 2021; PubMed: 34673030; DOI: 10.1016/j.jbc.2021.101308

Experimental method

X-RAY DIFFRACTION (1.9 Å)