6VTQ
Crystal structure of G16C human Galectin-7 mutant in complex with lactose
Summary for 6VTQ
Entry DOI | 10.2210/pdb6vtq/pdb |
Related PRD ID | PRD_900008 |
Descriptor | Galectin-7, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, GLYCEROL, ... (4 entities in total) |
Functional Keywords | human galectin-7, lactose, g16c mutant, disulfide bond, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 30924.66 |
Authors | Pham, N.T.H.,Calmettes, C.,Doucet, N. (deposition date: 2020-02-13, release date: 2021-08-25, Last modification date: 2023-11-15) |
Primary citation | Pham, N.T.H.,Letourneau, M.,Fortier, M.,Begin, G.,Al-Abdul-Wahid, M.S.,Pucci, F.,Folch, B.,Rooman, M.,Chatenet, D.,St-Pierre, Y.,Lague, P.,Calmettes, C.,Doucet, N. Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. J.Biol.Chem., 297:101308-101308, 2021 Cited by PubMed: 34673030DOI: 10.1016/j.jbc.2021.101308 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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