6VTO
Crystal structure of human Galectin-7 in complex with 4-O-beta-D-Galactopyranosyl-D-glucose
Summary for 6VTO
Entry DOI | 10.2210/pdb6vto/pdb |
Descriptor | Galectin-7, (2~{R},3~{R},4~{R},5~{R})-4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,3,5, 6-tetrakis(oxidanyl)hexanal (3 entities in total) |
Functional Keywords | human galectin-7, lactose-furanose, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 30616.29 |
Authors | Pham, N.T.H.,Calmettes, C.,Doucet, N. (deposition date: 2020-02-13, release date: 2021-08-25, Last modification date: 2023-10-11) |
Primary citation | Pham, N.T.H.,Letourneau, M.,Fortier, M.,Begin, G.,Al-Abdul-Wahid, M.S.,Pucci, F.,Folch, B.,Rooman, M.,Chatenet, D.,St-Pierre, Y.,Lague, P.,Calmettes, C.,Doucet, N. Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. J.Biol.Chem., 297:101308-101308, 2021 Cited by PubMed: 34673030DOI: 10.1016/j.jbc.2021.101308 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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