6V7H
Structure of CTX-M-14 bound to Vaborbactam at 1.0 A
Summary for 6V7H
Entry DOI | 10.2210/pdb6v7h/pdb |
Descriptor | Beta-lactamase, Vaborbactam, 2-[(3~{R},6~{S})-2,2-bis(oxidanyl)-3-(2-thiophen-2-ylethanoylamino)-1-oxa-2-boranuidacyclohex-6-yl]ethanoic acid, ... (6 entities in total) |
Functional Keywords | esbl, boronate, beta-lactamase, inhibitor, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 57552.69 |
Authors | Pemberton, O.A.,Chen, Y. (deposition date: 2019-12-08, release date: 2020-08-12, Last modification date: 2023-10-11) |
Primary citation | Pemberton, O.A.,Tsivkovski, R.,Totrov, M.,Lomovskaya, O.,Chen, Y. Structural Basis and Binding Kinetics of Vaborbactam in Class A beta-Lactamase Inhibition. Antimicrob.Agents Chemother., 64:-, 2020 Cited by PubMed: 32778546DOI: 10.1128/AAC.00398-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
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